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COMMUNICATIONS TO THE EDITOR
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1557-1560
| 1'-Benzyl-3,4-dihydrospiro[2H-1- benzothiopyran-2,4'-piperidine] (Spipethiane), a Potent and Highly Selective  1 Ligand
Wilma Quaglia,
Mario Giannella,
Alessandro Piergentili,
Maria Pigini,
Livio Brasili,
Rosanna Di Toro,
Lorena Rossetti,
Santi Spampinato, and
Carlo Melchiorre
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EXPEDITED ARTICLES
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1561-1567
| Potent, Selective, and Orally Bioavailable Tricyclic Pyridyl Acetamide N-Oxide Inhibitors of Farnesyl Protein Transferase with Enhanced in Vivo Antitumor Activity
F. George Njoroge,
Bancha Vibulbhan,
Patrick Pinto,
W. Robert Bishop,
Mathew S. Bryant,
Amin A. Nomeir,
C.-C. Lin,
Ming Liu,
Ronald J. Doll,
V. Girijavallabhan, and
Ashit K. Ganguly
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1568-1573
| 5-(5,6-Dichloro-2-indolyl)-2-methoxy-2,4-pentadienamides: Novel and Selective Inhibitors of the Vacuolar H+-ATPase of Osteoclasts with Bone Antiresorptive Activity
Stefania Gagliardi,
Guy Nadler,
Emanuela Consolandi,
Carlo Parini,
Marcel Morvan,
Marie-Nöelle Legave,
Pietro Belfiore,
Andrea Zocchetti,
Geoffrey D. Clarke,
Ian James,
Ponnal Nambi,
Maxine Gowen, and
Carlo Farina
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ARTICLES
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1574-1580
| (+)-cis-N-Ethyleneamino-N-normetazocine Derivatives. Novel and Selective Ligands with Antagonist Properties
Giuseppe Ronsisvalle,
Agostino Marrazzo,
Orazio Prezzavento,
Lorella Pasquinucci,
Franco Vittorio,
Valeria Pittalà,
Maria S. Pappalardo,
Silvia Cacciaguerra, and
Santi Spampinato
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1581-1597
| Cyclopropane-Derived Peptidomimetics. Design, Synthesis, Evaluation, and Structure of Novel HIV-1 Protease Inhibitors
Stephen F. Martin,
Gordon O. Dorsey,
Todd Gane, and
Michael C. Hillier
, Horst Kessler,
Matthias Baur, and
Barbara Mathä
, John W. Erickson,
T. Nagarajan Bhat,
Sanjeev Munshi,
Sergei V. Gulnik, and
Igor A. Topol
[Full Article -
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1598-1612
| Novel and Selective 5-HT2C/2B Receptor Antagonists as Potential Anxiolytic Agents: Synthesis, Quantitative Structure-Activity Relationships, and Molecular Modeling of Substituted 1-(3-Pyridylcarbamoyl)indolines
Steven M. Bromidge,
Steven Dabbs,
David T. Davies,
D. Malcolm Duckworth,
Ian T. Forbes,
Peter Ham,
Graham E. Jones,
Frank D. King,
Damian V. Saunders,
Susannah Starr,
Kevin M. Thewlis,
Paul A. Wyman,
Frank E. Blaney,
Christopher B. Naylor,
Fiona Bailey,
Thomas P. Blackburn,
Vicky Holland,
Guy A. Kennett,
Graham J. Riley, and
Martyn D. Wood
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1613-1618
| Synthesis and Adrenergic Activity of a New Series of N-Aryl Dicyclopropyl Ketone Oxime Ethers: SAR and Stereochemical Aspects
Madeleine Blanc,
Abderrafii Tamir,
Silvère Aubriot,
Marie Claude Michel,
Mohamed Bouzoubaa,
Gérard Leclerc, and
Pierre Demenge
[Full Article -
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1619-1630
| Novel Euglycemic and Hypolipidemic Agents. 1
Braj B. Lohray,
Vidya Bhushan,
Bheema P. Rao,
Gurram R. Madhavan,
Nagabelli Murali,
Krovvidi N. Rao,
Ananth K. Reddy,
Bagepalli M. Rajesh,
Pamulapati G. Reddy,
Ranjan Chakrabarti,
Reeba K. Vikramadithyan,
Ramanujam Rajagopalan,
Rao N. V. S. Mamidi,
Hemant K. Jajoo, and
Swaminathan Subramaniam
[Full Article -
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1631-1640
| Syntheses and Biological Evaluation of Indolocarbazoles, Analogues of Rebeccamycin, Modified at the Imide Heterocycle
Pascale Moreau,
Fabrice Anizon,
Martine Sancelme,
Michelle Prudhomme,
Christian Bailly,
Carolina Carrasco,
Monique Ollier,
Danièle Sevère,
Jean-François Riou,
Doriano Fabbro,
Thomas Meyer, and
Anne-Marie Aubertin
[Full Article -
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1641-1650
| Synthesis and Biology of the Conformationally Restricted ACPD Analogue, 2-Aminobicyclo[2.1.1]hexane-2,5-dicarboxylic Acid-I, a Potent mGluR Agonist
Alan P. Kozikowski,
Darryl Steensma,
Gian Luca Araldi,
Werner Tückmantel,
Shaomeng Wang,
Sergey Pshenichkin,
Elena Surina, and
Jarda T. Wroblewski
[Full Article -
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1651-1659
| Anhydrolide Macrolides. 1. Synthesis and Antibacterial Activity of 2,3-Anhydro-6-O-methyl 11,12-Carbamate Erythromycin A Analogues
Richard L. Elliott,
Daisy Pireh,
George Griesgraber,
Angela M. Nilius,
Patty J. Ewing,
Mai Ha Bui,
Patti M. Raney,
Robert K. Flamm,
Ki Kim,
Rodger F. Henry,
Daniel T. W. Chu,
Jacob J. Plattner, and
Yat Sun Or
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1660-1670
| Anhydrolide Macrolides. 2. Synthesis and Antibacterial Activity of 2,3-Anhydro-6-O-methyl 11,12-Carbazate Erythromycin A Analogues
George Griesgraber,
Mark J. Kramer,
Richard L. Elliott,
Angela M. Nilius,
Patty J. Ewing,
Patti M. Raney,
Mai-Ha Bui,
Robert K. Flamm,
Daniel T. W. Chu,
Jacob J. Plattner, and
Yat Sun Or
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1671-1678
| Modular Fluorescent-Labeled Siderophore Analogues
Raphael Nudelman,
Orly Ardon,
Yitzhak Hadar,
Yona Chen,
Jacqueline Libman, and
Abraham Shanzer
[Full Article -
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1679-1687
| Conformationally Defined Retinoic Acid Analogues. 4. Potential New Agents for Acute Promyelocytic and Juvenile Myelomonocytic Leukemias
Donald D. Muccio,
Wayne J. Brouillette,
Theodore R. Breitman,
Mohammed Taimi,
Peter D. Emanuel,
Xiao-kun Zhang,
Guo-quan Chen,
Brahma P. Sani,
Pratap Venepally,
Lakshmi Reddy,
Muzaffar Alam,
Linda Simpson-Herren, and
Donald L. Hill
[Full Article -
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1688-1695
| Antineoplastic Agents. 379. Synthesis of Phenstatin Phosphate1a,
George R. Pettit,
Brian Toki,
Delbert L. Herald,
Pascal Verdier-Pinard,1b
Michael R. Boyd,1b
Ernest Hamel, and
Robin K. Pettit
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1696-1701
| Inhibition of Human Alcohol Dehydrogenases by Formamides
John F. Schindler,
Kristine B. Berst, and
Bryce V. Plapp
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1702-1707
| Isosteric Analogues of Nicotinamide Adenine Dinucleotide Derived from Furanfurin, Thiophenfurin, and Selenophenfurin as Mammalian Inosine Monophosphate Dehydrogenase (Type I and II) Inhibitors
Palmarisa Franchetti,
Loredana Cappellacci,
Paolo Perlini,
Hiremagalur N. Jayaram,
Adrian Butler,
Bryan P. Schneider,
Frank R. Collart,
Eliezer Huberman, and
Mario Grifantini
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1708-1715
| 2'-C-Methyl Analogues of Selective Adenosine Receptor Agonists: Synthesis and Binding Studies
Palmarisa Franchetti,
Loredana Cappellacci,
Stefano Marchetti,
Letizia Trincavelli,
Claudia Martini,
Maria R. Mazzoni,
Antonio Lucacchini, and
Mario Grifantini
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1716-1728
| A Potent, Orally Bioavailable Benzazepinone Growth Hormone Secretagogue
Robert J. DeVita,
Richard Bochis,
Alison J. Frontier,
Andrew Kotliar,
Michael H. Fisher,
William R. Schoen,
Matthew J. Wyvratt,
Kang Cheng,
Wanda W.-S. Chan,
Bridget Butler,
Thomas M. Jacks,
Gerard J. Hickey,
Klaus D. Schleim,
Kwan Leung,
Zhesheng Chen,
S.-H. Lee Chiu,
William P. Feeney,
Paul K. Cunningham, and
Roy G. Smith
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1729-1740
| Novel Thieno[2,3-d][1,3]oxazin-4-ones as Inhibitors of Human Leukocyte Elastase
Michael Gütschow and
Ulf Neumann
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